iO Calming Paste is a nutritional supplement for horses to increase dietary intake of L-Tryptophan, Vitamins B1, B2, B6 and magnesium where levels may be low. Magnesium plays an important role in stress management for horses. B Vitamins also have many benefits, including insect management. Double-dose per tube! Controls & Prevents: Proven to calm nervous horses. Provides supplementation of B-Group vitamins not readily stored in the body. Known to rectify nervous twitching, flighty behaviour, difficult behaviour and nervous related diarrhoea. Withholding Period: NIL Dose Rates & Administration Instructions: Give 20mL daily (based on 500-600kg adult horse) preferably within 4 hours of travel or exercise, or as directed by a veterinary surgeon. Rate of Use: Adult Horse (500-600kg). Active Constituent: Each ML Contains: L-Tryptophan 300mg, Magnesium Proteinate 100mg, Thiamine HCI (Vitamin B1) 100mg, Riboflavin (Vitamin B2) 20mg, Pyridoxine HCI (Vitamin B6) 10mg.